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GOSH researchers grow world’s first functioning oesophagus

Funding from Great Ormond Street Hospital Children’s Charity has supported a pioneering new study undertaken by researchers from Great Ormond Street Hospital (GOSH) and The Francis Crick Institute, which has seen scientists grow the world’s first oesophagus, that has been engineered from stem cells and successfully transplanted into mice. The results have been published in the Nature Communications journal today (Tuesday 16 October).

Eight Nights of Fundraising: Our GOSH Chanukah Appeal

Help us bring light to seriously ill children this Chanukah

Across the eight nights of Chanukah, we’re asking Great Ormond Street Hospital (GOSH) supporters – including you – to raise funds to support our incredible Play team.

Games are an essential part of Chanukah fun, but play is even more important when a child is seriously ill. Our Play team provides care that goes beyond the medical needs of each child, providing an opportunity for children to work through any emotions and worries they have about being in hospital.

Out of the bubble

Henry has severe combined immunodeficiency (SCID), a group of rare, inherited disorders that affect the immune system. Patients like Henry often have to live in a sterile environment with a barrier between them and the outside world, giving rise to the term ‘bubble baby’ syndrome.

Henry was given a 10% chance of survival, until a bone marrow transplant from his older brother dramatically improved his condition. Henry’s mum, Maria, and three members of staff at GOSH who were instrumental in his care, share his story.

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Meet GOSH's Chaplaincy and Spiritual Care team

In Paul O’Grady’s Little Heroes, we're given a tour of the Grade 2 listed St Christopher’s Chapel. Completed in 1875, the chapel moved – en bloc – during the redevelopment of the old hospital in the late 1980s to the spot it occupies today. To find out more about the Chaplaincy and Spiritual Care team itself, we speak with Senior Chaplain Jim Linthicum and Deputy Senior Chaplain Dorothy Moore Brooks to hear their story.

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Lynsey Steele - Play Specialist

During Paul O’Grady’s Little Heroes, we’re shining a spotlight on the wonderful staff across the hospital who help children get better and fulfil their potential. Lynsey Steele is a play specialist supporting children staying at Great Ormond Street Hospital (GOSH). Lynsey helps them understand and prepare for treatment or operations through play.
Little Hero, George, in corridor

Little Hero – George

When he was seven years old, George was diagnosed with hypertrophic cardiomyopathy a condition that's very rare in children, with only a few hundred people in the UK developing it in childhood. Here his mum, Serena, tells their story. 

Little Hero – Angel

When Angel was three months old, doctors in Peterborough discovered she had tumors in both her kidneys. Unfortunately, chemotherapy was unsuccessful, so she had to have both kidneys removed at Great Ormond Street Hospital (GOSH). She now relies on dialysis to keep her healthy while she waits on the transplant list. Her mum Honey shares her story.