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Sixth Clinical Research Starter Grant Funding Call

Great Ormond Street Hospital Children’s Charity’s mission is to enhance Great Ormond Street Hospital’s (GOSH) ability to transform the health and wellbeing of children and young people, giving them the best chance to fulfil their potential. The sixth funding call for the charity’s Clinical Research Starter Grants has now launched. The deadline for applications is 5pm Thursday 14 December 2017. 

Scope of call

The charity is inviting clinically focused pilot or feasibility studies that will answer research questions to help improve care and health service delivery at GOSH. These grants are designed to enable investigators to gather the proof-of-concept data needed to move the research to the next stage. This is intended to be pump-prime funding and applicants will need to outline how they will leverage the charity grant to obtain funding from the National Institute of Health Research (NIHR) or another external funding body.

We particularly encourage proposals that:

  • Conduct research to optimise and/or improve delivery of health services provided by GOSH, aim to fill a clear evidence gap or are likely to lead to changes in practice.
  • Evaluate the effectiveness of interventions and/or scrutinise innovations and developments.
  • Are highly translational and likely to benefit patients directly and address problems that will have an impact at the point-of-care.
  • Make the most of the unique patient population at GOSH.
  • Demonstrate real clinical and academic, multidisciplinary partnership from staff groups across the entire spectrum such as medical, nursing, allied health professions, pharmacy and scientific.
  • Are submitted by early career researchers and those who are still consolidating their independent research careers.

All applications must be hypothesis-driven and applicants should clearly outline the research question the study aims to answer. Applicants are reminded of the importance of clearly defining the study as a feasibility or pilot study (as defined by the NIHR). and demonstrating a clear pathway to the next phase of research beyond the end of charity funding.

We will not consider applications under this scheme for proposals that:

  • Aim to identify causes of disease
  • Aim to establish audits, databases and registries or are mainly service development

Funding available

Up to £500,000 is available to spend under this call and it is anticipated that we will fund a range of proposals from different investigators. Projects of up to 18 months duration will be considered, to a maximum cost of £100,000. Lead applicants must be research active GOSH health professionals based at GOSH. Funding will be provided for the direct costs of research (such as research staff and consumables) and will not cover consultant PA’s or team-leader salary time.


To submit an application please visit our online application system or use the button below.

Apply online

The deadline for submission of preliminary applications is 5pm Thursday 14 December 2017.

If you have any questions please email


As part of the call this year the charity will also be running a funding workshop. You are encouraged to attend to find out more about the scope of the call, the types of applications that the charity aims to support through this funding scheme and what the charity expects to see in applications. Details of the workshop can be found below:

Date and time: 2pm Tuesday 31 October 2017

Speakers:  Great Ormond Street Hospital Children's Charity, a member of the charity’s Research Assessment Panel and the R&D Team

Audience: Those interested in conducting clinical research at GOSH and UCL Great Ormond Street Institute of Child Health (ICH) and who plan to submit an application. Attendees across all staff groups such as medical, nursing, allied health professions, pharmacy and scientific with all levels of experience are welcomed.

Location:  Levinsky Room, ICH, 30 Guilford Street, WC1N 1EH

The sessions will cover: 

  • The remit of the call and the types of applications the charity is looking to support
  • Thoughts from a member of the charity’s Research Assessment Panel
  • Useful resources

If you would like to attend the session, please register your interest at Eventbrite.

Dr Simon Newell Early Career Investigator of the Year Award 2018

Apply via the Royal College of Paediatrics and Child Health (RCPCH) website

Since 1999, Sparks has funded an annual award that recognises excellence in the field of paediatric research. The award is offered in partnership with the  RCPCH to recognise an outstanding young medically qualified researcher in British paediatrics.

In February 2017 Sparks joined GOSH Charity and became part of the GOSH Charity family, so this award is now facilitated by GOSH Charity.

Sparks Children's Medical ResearchGOSH-Sparks_kitemark_blue 
Royal College of Paediatrics and Child Health Leading the way in Children's Health

Previously this was known as the Young Investigator of the Year Award. This year the award has been re-named in memory of Dr Simon Newell – a renowned and widely respected neonatologist and paediatrician who had a passion to encourage the next generation of paediatric clinicians and researchers. He made an enormous contribution to neonatal medicine across the UK and was a great advocate for paediatric health. Simon was connected to Sparks throughout his career, first as a researcher, then a member of the Medical Advisory Committee and later a Trustee.

This award has been named in his memory and as recognition of the tremendous work he did.

The award

  • A trophy
  • £1,000 for the winner
  • £1,000 to the winner’s department to buy equipment and cover other expenses such as consumables connected with their research.

The RCPCH presents the winner at the RCPCH Conference in May 2017. The winner will be notified ahead of the conference and the RCPCH will cover the winner’s travel and conference costs.

The nomination process is managed by the RCPCH. To access the forms please visit the RCPCH website.

For more information or if you have any questions, please contact the RCPCH Research and Evaluation team on

We welcome applications from early career researchers who have not yet completed or who may have recently completed their certificates of completion of training (CCT). Nominees may nominate themselves with the support of a senior member of staff.

Friday 24 November 2017

Previous winners

Dr Chris Moxon, The University of Liverpool (2017)
The 2017 award was granted to Dr Chris Moxon, Clinical Lecturer in Paediatrics in the Department of Clinical Infection, Microbiology and Immunology at the University of Liverpool. Dr Moxon was recognised for his groundbreaking work on malaria – a disease that claims the life of half a million children worldwide every year.

His work particularly focuses on the most severe complication of malaria – cerebral malaria – where the infection affects the brain causing swelling and coma.

Up to a quarter of children with cerebral malaria lose their lives and children that do survive are often left with significant disability.

Dr Moxon’s research is tackling this by trying to understand which children go on to develop brain complications, why malaria targets the brain and not other organs, and the exact mechanisms by which malaria causes the damage in the brain.

With this understanding, he hopes to develop new, more effective treatments to stop the devastating effect of this disease. He also hopes this work will help better understand other brain infections.

He says “It is a huge honour to win this award – to me and to all the people that I have worked with. It also means a lot to me that RCPCH and Sparks have given this award for work on malaria – a disease of huge global importance for child health but that we see infrequently here in the UK.”

More winners

2016 Dr Manish Sadarangani
2015 Dr Robert Phillps
2014 Dr Marc Tebruegge
2013 Dr Roderick Mitchell and Dr Anthony Wiskin (jointly awarded)
2012 Dr Matthew Murray
2011 Dr Andrew Prendergast
2010 Dr Don Sharkey
2009 Dr Richard F M Chin
2006 Dr Amanda Drake
2005 Dr Howard Clark
2004 Dr Mark Herbert
2003 Dr Deborah Tweddle
2002 Dr Jugnoo Rahi
2001 Dr Paul Winyard
2000 Dr Richard Gilbertson
1999 Dr Jeremy Hull