Funded Paediatric Cancer Clinical Trials

In 2025, GOSH Charity launched the National Paediatric Cancer Clinical Trial Fund to support early phase clinical trials and translational research testing new targeted therapies for children and young people with the hardest to treat cancers.

Below is a list of the projects funded through this grant scheme. If you have any questions about any of the projects, please get in touch with the GOSH Charity Grants Team.

National Paediatric Cancer Clinical Trial Fund 2025/26

In 2026, two clinical trials received funding, totalling over £7.5 million.

Lead Investigator Institution Programme Title Total
Dr Karin Straathof UCL Cancer Institute / Great Ormond Street Hospital Next-generation CAR T-cell therapy for children and young people with relapsed sarcoma (MIGHTier) £2,765,942
Professor Persis Amrolia UCL Great Ormond Street Institute of Child Health / Great Ormond Street Hospital First-in-human clinical trial for relapsed and refractory acute myeloid leukaemia in children and young people (FIESTA) £4,826,028